Polycythaemia vera

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Peripheral gangrene in polycythaemia vera.

well account for the phonocardiographic features of extreme variability of the A2-OC interval and the intermittent absence of the OC. The systolic murmur was in keeping with mitral reflux with its rate related variability. In a very ill patient with a malfunctioning mitral Starr-Edwards prosthesis we feel that the phonocardiographic findings can be a useful bedside adjunct to the physician and ...

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Joint Complaints in Polycythaemia Vera.

The reported incidence of gout and hyperuricaemia in polycythaemia vera has varied in different series. Thus Tinney, Polley, Hall, and Giffin (1945) reported clinical gout in 4 7 per cent. of 168 cases, Videbaek (1950) in 9 per cent. of 125 cases, and Lawrence, Berlin, and Huff (1953) in 7 per cent. of 159 patients, and unspecified arthritis in a further 14 per cent. On the other hand, Wasserma...

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Masked polycythaemia vera is genetically intermediate between JAK2V617F mutated essential thrombocythaemia and overt polycythaemia vera

Polycythaemia vera (PV) can be defined as a myeloproliferative neoplasm (MPN) with erythrocytosis and JAK2V617F (or an equivalent marker of clonality). While these simple criteria are sufficient for most cases of overt PV, an estimated 10–15% of PV patients do not have an elevated haemoglobin concentration (Hb) and may mimic JAK2-positive essential thrombocythaemia (ET). This poses a problem fo...

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Extramedullary haemopoietic tumours complicating polycythaemia vera.

A 52 year old man with newly diagnosed polycythaemia vera in proliferative phase developed widespread extramedullary haemopoiesis (EMH), and died as a result of cervical cord compression. At necropsy, microscopic areas of primitive cells characteristic of granulocytic sarcoma were found within a large tumour of EMH in the right retroperitoneal region. Ultrastructural analysis showed unusual hex...

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Reno-vascular disease in polycythaemia rubra vera.

Hypertension and polycythaemia rubra vera commonly occur in the same patient. This is regarded as coincidence and the hypertension does not respond to correction of polycythaemia. We report a case of renal artery stenosis occurring simultaneously with polycythaemia rubra vera and suggest that renovascular occlusive disease should be excluded in such patients with refractory hypertension.

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ژورنال

عنوان ژورنال: Swiss Medical Forum ‒ Schweizerisches Medizin-Forum

سال: 2013

ISSN: 1424-4020,1424-3784

DOI: 10.4414/smf.2013.01716